Virus structures: Those magnificent molecular machines

Virus structures: Those magnificent molecular machines

Double-stranded RNA viruses face two major problems: the endogenous machinery of its host cells does not replicate RNA genomes, and double-stranded RNA provokes strong cellular defence responses such as interferon induction and gene silencing. The solution for the virus is to keep the genomic double-stranded RNA always in a separate container, an icosahedral viral capsid, and to more-or-less au...

Those magnificent molecular machines: logistics in dsRNA virus transcription.

Double-stranded (ds) RNA viruses face two major challenges when infecting a cell: the cellular replicative machinery does not operate on dsRNA genomes, and dsRNA provokes a strong apoptotic response. To overcome these problems, dsRNA viruses conceal their genomes from the host cell in an enclosed icosahedral viral core, but then need to carry with them all the necessary enzymatic requirements f...

Those magnificent men and their flying machines.

Spotlight: Catalytic applications of molecular machines

Morteza Torabi was born in 1995 in Hamedan, Iran. He received his B.Sc. in Applied Chemistry (2017) and M.Sc. in Organic Chemistry (2019) from Bu-Ali Sina University under the supervision of Professor Mohammad Ali Zolfigol. He is currently working towards his Ph.D. under the supervision of Professor Mohammad Ali Zolfigol at Bu-Ali Sina University. His research interest is the design, synthesis ...

A magnificent time with the "magnificent seven" transmembrane spanning receptors.

A Magnificent Time With the ''Magnificent Seven'' Transmembrane Spanning Receptors Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2003 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/01.RES.0000061771.61280.B8 2003;92:342-344 Circ Res. http://circres.ahajou...